Introduction: Severe acute respiratory syndrome coronavirus Liquid Soap 2 (SARS-CoV-2) is a positive-sense single-strand RNA virus belonging to the Coronaviridae family, responsible for coronavirus infectious disease 2019 (COVID-19) with the rapid transmission.This study aimed to characterize and compare SARS-CoV-2 and SARS-CoV major viral proteins
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Both TRPA1 and purinergic P2X receptors have been proposed as potential targets for the treatment of visceral pain.We found that the intracolonic administration of a low dose mustard oil (0.5%), a well-known TRPA1 agonist, produced nociceptive responses and abdominal wall referred mechanical hyperalgesia, without inducing apparent tissue damage.Bot